This issue of the Veterinary Clinics of North America: Food Animal Practice focuses on infectious bovine keratoconjunctivitis (IBK). IBK is the most important ocular disease of cattle because of its impact on animal health, animal well-being, the antibiotic usage treatment required, and its effect on production. Top experts address Defining and Diagnosing Infectious Bovine Keratoconjunctivitis, Applying Concepts of Causal Inference, The Role of Environmental Factors in the Epidemiology, and more.