Cell Therapy Against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials
Editat de Kiyohiro Houkin, Koji Abe, Satoshi Kurodaen Limba Engleză Hardback – 12 ian 2017
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.
Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
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Specificații
ISBN-13: 9784431560579
ISBN-10: 4431560572
Pagini: 120
Ilustrații: X, 156 p. 15 illus., 11 illus. in color.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.46 kg
Ediția:1st ed. 2017
Editura: Springer
Colecția Springer
Locul publicării:Tokyo, Japan
ISBN-10: 4431560572
Pagini: 120
Ilustrații: X, 156 p. 15 illus., 11 illus. in color.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.46 kg
Ediția:1st ed. 2017
Editura: Springer
Colecția Springer
Locul publicării:Tokyo, Japan
Cuprins
Part I. Optimal Cell Sources .- 1. Bone Marrow-Derived Mononuclear Cells .- 2. Mesenchymal Stem Cells / Bone Marrow Stromal Cells .- 3. Neural Stem Cells / Neuronal Progenitor Cells.- 4. iPS Cells / iN .- Part II. Translational Research.- 5. Cell Culture.- 6. Cell Dose, Timing and Route.- 7. Scaffold.- 8. Cell Tracking .- 9. Functional Bio-Imaging .- Part III. Clinical Trials .- 10. Review of Previous Clinical Trials and Guideline of Cell Therapy.- 11. Bone Marrow-Derived Mononuclear Cells.- 12. Mesenchymal Stem Cells.
Notă biografică
Dr. Kiyohiro Houkin, Department of Neurosurgery, Hokkaido University
Dr. Koji Abe, Department of Neurology, Okayama University
Dr. Satoshi Kuroda, Department of Neurosurgery, University of Toyama
Textul de pe ultima copertă
This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.
Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.
Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
Caracteristici
Describes the current state of knowledge on cell therapy for cerebral stroke
Addresses comprehensive topics in both basic research and clinical trials
Written by experts with considerable personal experience in neurosurgery and neurology
Addresses comprehensive topics in both basic research and clinical trials
Written by experts with considerable personal experience in neurosurgery and neurology