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Cell Therapy Against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials

Editat de Kiyohiro Houkin, Koji Abe, Satoshi Kuroda
en Limba Engleză Paperback – 12 iul 2018
This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.

Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
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Specificații

ISBN-13: 9784431567660
ISBN-10: 4431567666
Pagini: 156
Ilustrații: X, 156 p. 15 illus., 11 illus. in color.
Dimensiuni: 155 x 235 x 5 mm
Greutate: 0.09 kg
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer
Colecția Springer
Locul publicării:Tokyo, Japan

Cuprins

Part I. Optimal Cell Sources .- 1. Bone Marrow-Derived Mononuclear Cells .- 2. Mesenchymal Stem Cells / Bone Marrow Stromal Cells .- 3. Neural Stem Cells / Neuronal Progenitor Cells.- 4. iPS Cells / iN .- Part II. Translational Research.- 5. Cell Culture.- 6. Cell Dose, Timing and Route.- 7. Scaffold.- 8. Cell Tracking .- 9. Functional Bio-Imaging .- Part III. Clinical Trials .- 10. Review of Previous Clinical Trials and Guideline of Cell Therapy.- 11. Bone Marrow-Derived Mononuclear Cells.- 12. Mesenchymal Stem Cells.

Notă biografică

Dr. Kiyohiro Houkin, Department of Neurosurgery, Hokkaido University
Dr. Koji Abe, Department of Neurology, Okayama University
Dr. Satoshi Kuroda, Department of Neurosurgery, University of Toyama

Textul de pe ultima copertă

This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke.
Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity.

Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy.
The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.

Caracteristici

Describes the current state of knowledge on cell therapy for cerebral stroke
Addresses comprehensive topics in both basic research and clinical trials
Written by experts with considerable personal experience in neurosurgery and neurology