Cantitate/Preț
Produs
Total produse
Vezi coșul
Channelrhodopsin: Methods and Protocols de Robert E. Dempski

Channelrhodopsin: Methods and Protocols: Methods in Molecular Biology, cartea 2191

Editat de Robert E. Dempski
en Limba Engleză Paperback – sep 2021
This book merges approaches in understanding the function of the light-gated ion channels known as channelrhodopsin together with methods addressing how channelrhodopsins can be used to address biomedical questions on a cellular or organismal level. Since the first molecular identification of channelrhodopsins, a broad range of tools have been created and new approaches developed to both better understand the molecular determinants of channelrhodopsin function as well as to use these and homologous proteins from a variety of species as tools to better understand physiological processes, which this volume addresses. Additionally, channelrhodopsins have become instrumental as a potential treatment for disease states. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Channelrhodopsin: Methods and Protocols provides a resource for those interested in honing their current expertise in this vital area of study as well as potentially branching out into new directions.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 70796 lei  6-8 săpt.
  Springer Us – sep 2021 70796 lei  6-8 săpt.
Hardback (1) 96155 lei  6-8 săpt.
  Springer Us – sep 2020 96155 lei  6-8 săpt.

Din seria Methods in Molecular Biology

Preț: 70796 lei

Preț vechi: 83289 lei
-15% Nou

Puncte Express: 1062
Preț estimativ în valută:
13550€ • 14093$ • 11355£

Carte tipărită la comandă

Livrare economică 14-28 martie

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781071608326
ISBN-10: 1071608320
Pagini: 405
Ilustrații: XII, 405 p. 117 illus., 99 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 0.73 kg
Ediția:1st ed. 2021
Editura: Springer Us
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:New York, NY, United States

Cuprins

Molecular Dynamics Simulations of Channelrhodopsin Chimera, C1C2.- Computing Potential of the Mean Force Profiles for Ion Permeation through Channelrhodopsin Chimera, C1C2.- Nanodisc Reconstitution of Channelrhodopsins Heterologously Expressed in Pichia pastoris for Biophysical Investigations.- Characterizing Channelrhodopsin Channel Properties via Two-Electrode Voltage Clamp and Kinetic Modeling.- Charge Transport by Light-Activated Rhodopsins Determined by Electrophysiological Recordings.- Probing Channelrhodopsin Electrical Activity in Algal Cell Populations.- Two-Photon Optogenetic Stimulation of Drosophila Neurons.- Probing Synaptic Signaling with Optogenetic Stimulation and Genetically-Encoded Calcium Reporters.- Optogenetics to Interrogate Neuron-Glia Interactions in Pups and Adults.- Chronic Optogenetic Pacing of Human Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues.- Patterned Optogenetic Stimulation Using a DMD-Projector.- Selecting ChannelrhodopsinConstructs for Optimal Visual Restoration in Differing Light Conditions.- Recording Channelrhodopsin-Evoked Field Potentials and Startle Responses from Larval Zebrafish.- Automated Functional Screening for Modulators of Optogenetically-Activated Neural Responses in Living Organisms.- Optogenetic Interrogation of ChR2-Expressing GABAergic Interneurons after Transplantation into the Mouse Brain.- Application of Targeting-Optimized Chronos for Stimulation of the Auditory Pathway.- Channelrhodopsins for Cell-Type Specific Illumination of Cardiac Electrophysiology.- Optogenetic Control of Cardiac Autonomic Neurons in Transgenic Mice.- Dissecting Mechanisms of Motivation within the Nucleus Accumbens Using Optogenetics.- Optogenetic Stimulation of the Central Amygdala Using Channelrhodopsin.- Optical Manipulation of Perfused Mouse Heart Expressing Channelrhodopsin-2 in Rhythm Control.- Chronic Optogenetic Stimulation in Freely-Moving Rodents.

Textul de pe ultima copertă

This book merges approaches in understanding the function of the light-gated ion channels known as channelrhodopsin together with methods addressing how channelrhodopsins can be used to address biomedical questions on a cellular or organismal level. Since the first molecular identification of channelrhodopsins, a broad range of tools have been created and new approaches developed to both better understand the molecular determinants of channelrhodopsin function as well as to use these and homologous proteins from a variety of species as tools to better understand physiological processes, which this volume addresses. Additionally, channelrhodopsins have become instrumental as a potential treatment for disease states. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Channelrhodopsin: Methods and Protocols provides a resource for those interested in honing their current expertise in this vital area of study as well as potentially branching out into new directions.

Caracteristici

Includes cutting-edge techniques Provides step-by-step detail essential for reproducible results Contains key implementation advice from the experts