Cantitate/Preț
Produs
Total produse
Vezi coșul
Duchenne Muscular Dystrophy: Methods and Protocols de Camilla Bernardini

Duchenne Muscular Dystrophy: Methods and Protocols: Methods in Molecular Biology, cartea 1687

Editat de Camilla Bernardini
en Limba Engleză Hardback – 25 oct 2017
This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshootingand avoiding known pitfalls. 

Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 71744 lei  38-44 zile
  Springer – 23 aug 2018 71744 lei  38-44 zile
Hardback (1) 108875 lei  6-8 săpt.
  Springer – 25 oct 2017 108875 lei  6-8 săpt.

Din seria Methods in Molecular Biology

  • 60% Nucleic Acid and Peptide Aptamers: Methods and Protocols
    Preț: 34795 lei
  • 23% Pheromone Signaling: Methods and Protocols
    Preț: 59856 lei
  • Engineering and Analyzing Multicellular Systems: Methods and Protocols
    Preț: 49679 lei
  • 20% Clinical Bioinformatics
    Preț: 88295 lei
  • Mitochondrial Regulation: Methods and Protocols
    Preț: 25204 lei
  • 5% Multiple Sclerosis: Methods and Protocols
    Preț: 71733 lei
  • 5% Bacterial Persistence: Methods and Protocols
    Preț: 71911 lei
  • 5% DNA-Protein Interactions: Principles and Protocols
    Preț: 72883 lei
  • 5% Methods in Mouse Atherosclerosis
    Preț: 73457 lei
  • 15% Cell Cycle Oscillators: Methods and Protocols
    Preț: 65228 lei
  • 18% TGF-β Signaling: Methods and Protocols
    Preț: 100802 lei
  • 5% Whole Genome Amplification: Methods and Protocols
    Preț: 72221 lei
  • 18% Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization
    Preț: 89877 lei
  • 15% Phospho-Proteomics: Methods and Protocols
    Preț: 65342 lei
  • 15% Candida Species: Methods and Protocols
    Preț: 64310 lei
  • 18% Induced Pluripotent Stem (iPS) Cells: Methods and Protocols
    Preț: 139083 lei
  • 5% Post-Transcriptional Gene Regulation
    Preț: 73010 lei
  • 20% In Vitro Embryogenesis in Higher Plants
    Preț: 82163 lei
  • 18% Yeast Functional Genomics: Methods and Protocols
    Preț: 95589 lei
  • 15% Statistical Analysis in Proteomics
    Preț: 64937 lei
  • 5% SiRNA Delivery Methods: Methods and Protocols
    Preț: 72598 lei
  • 18% Estrogen Receptors: Methods and Protocols
    Preț: 96831 lei
  • 5% Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II
    Preț: 72093 lei
  • Plant Bioinformatics: Methods and Protocols
    Preț: 39258 lei
  • 5% Breast Cancer: Methods and Protocols
    Preț: 73370 lei
  • 18% Endocannabinoid Signaling: Methods and Protocols
    Preț: 94642 lei
  • 23% Zebrafish: Methods and Protocols
    Preț: 86021 lei
  • 15% Activity-Based Proteomics: Methods and Protocols
    Preț: 64166 lei
  • 5% Drug Target miRNA: Methods and Protocols
    Preț: 103769 lei
  • 23% Computational Protein Design
    Preț: 88385 lei
  • SH2 Domains: Methods and Protocols
    Preț: 79216 lei
  • Cholesterol Homeostasis: Methods and Protocols
    Preț: 42362 lei
  • 5% The Immune Synapse: Methods and Protocols
    Preț: 42591 lei
  • Organ Regeneration: 3D Stem Cell Culture & Manipulation
    Preț: 59220 lei
  • 5% Innate Antiviral Immunity: Methods and Protocols
    Preț: 34562 lei
  • 19% Protein Engineering: Methods and Protocols
    Preț: 49188 lei
  • 5% Innate Immune Activation: Methods and Protocols
    Preț: 103884 lei
  • 5% Investigations of Early Nutrition Effects on Long-Term Health: Methods and Applications
    Preț: 52415 lei
  • 18% Planarian Regeneration: Methods and Protocols
    Preț: 208644 lei
  • 5% Epitope Mapping Protocols
    Preț: 127730 lei
  • Tissue Proteomics: Methods and Protocols
    Preț: 78993 lei
  • 5% Genetic Epidemiology: Methods and Protocols
    Preț: 133910 lei
  • 18% Plant Chemical Genomics: Methods and Protocols
    Preț: 136679 lei
  • 5% Lung Innate Immunity and Inflammation: Methods and Protocols
    Preț: 75266 lei
  • 5% Rational Drug Design: Methods and Protocols
    Preț: 37489 lei
  • 18% Microbiome Analysis: Methods and Protocols
    Preț: 137205 lei
  • 18% Computational Methods in Protein Evolution
    Preț: 111057 lei
  • 18% Electrophoretic Separation of Proteins: Methods and Protocols
    Preț: 138447 lei
  • 18% Microbial Metabolomics: Methods and Protocols
    Preț: 110593 lei
  • 18% SNAREs: Methods and Protocols
    Preț: 94998 lei

Preț: 108875 lei

Preț vechi: 114604 lei
-5% Nou

Puncte Express: 1633
Preț estimativ în valută:
20836€ • 21760$ • 17275£

Carte tipărită la comandă

Livrare economică 11-25 februarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781493973736
ISBN-10: 1493973738
Pagini: 288
Ilustrații: XII, 287 p. 49 illus., 34 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 0.74 kg
Ediția:1st ed. 2018
Editura: Springer
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:New York, NY, United States

Cuprins

An Overview of Recent Therapeutics Advances for Duchenne Muscular Dystrophy.- Clinical Manifestations and Overall Management Strategies for Duchenne Muscular Dystrophy.- Cardiac Involvement in Duchenne Muscular Dystrophy and Related Dystrophinopathies.- Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry.- Imaging Analysis of the Neuromuscular Junction in Dystrophic Muscle.- System Biology Approach: Gene Network Analysis for Muscular Dystrophy.- Proteomic Profiling of the Dystrophin-Deficient Brain.- Probing the Pathogenesis of Duchenne Muscular Dystrophy Using Mouse Models.- Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy.- Designing Effective Antisense Oligonucleotides for Exon Skipping.- Identification of Splicing Factors Involved in DMD Exon Skipping Events Using an In Vitro RNA Binding Assay.- The Use of Antisense Oligonucleotides for the Treatment of Duchenne Muscular Dystrophy.- PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment.- Proton Nuclear Magnetic Resonance (1H NMR) Spectroscopy-Based Analysis of Lipid Components in Serum / Plasma of Patients with Duchenne Muscular Dystrophy (DMD).- Test of Anti-Fibrotic Drugs in a Cellular Model of Fibrosis Based on Muscle-Derived Fibroblasts from Duchenne Muscular Dystrophy Patients.- Flow Cytometry-Defined CD49d Expression in Circulating T-Lymphocytes is a Biomarker for Disease Progression in Duchenne Muscular Dystrophy.- Advanced Methods to Study the Cross-Talk Between Fibro-Adipogenic Progenitors and Muscle Stem Cells.- AAV6 Vector Production and Purification for Muscle Gene Therapy.- From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method.

Textul de pe ultima copertă

This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshootingand avoiding known pitfalls. 

Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.

Caracteristici

Includes cutting-edge methods and protocols for DMD research Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts Includes supplementary material: sn.pub/extras