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Gene Delivery: Nanotechnology and Therapeutic Applications: Drugs and the Pharmaceutical Sciences

Editat de Yashwant Pathak
en Limba Engleză Paperback – 9 oct 2024
Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.
Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery.
Additional features include"
  • Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing.
  • Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize.
  • Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario
  • Discusses siRNA, mRNA, and DNA plasmids.

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Specificații

ISBN-13: 9781032029771
ISBN-10: 1032029773
Pagini: 246
Ilustrații: 44
Dimensiuni: 178 x 254 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Drugs and the Pharmaceutical Sciences

Locul publicării:Boca Raton, United States

Public țintă

Academic, Postgraduate, Professional, and Professional Practice & Development

Cuprins

Chapter 01
Challenges in delivering gene therapy
Chapter 02
Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systems
Chapter 03
Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy
Chapter 04
Green nanoparticles for oligonucleotide delivery
Chapter 05
Development of mRNA vaccines for Covid -19 in challenging Pandemic scenario
Chapter 06
Gene therapy for cardiovascular diseases: clinical evidences
Chapter 07
Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS
Chapter 08
siRNA delivery for therapeutic applications using nanoparticles
Chapter 09
Clinical perspectives on Gene therapy for retina and eye diseases
Chapter 10
Herpesvirus microRNAs for use in gene therapy immune-evasion strategies
Chapter 11
siRNA delivery for therapeutic applications using nanoparticles
Chapter 12
Gene therapy and small molecule treatment for cystic fibrosis
Chapter 13
CRISPR gene therapy recent trends and clinical applications
Chapter 14
Clinical applications of gene therapy for Immuno-deficiencies
Chapter 15
Regulatory challenges for nano gene delivery

Notă biografică

Dr. Yashwant Pathak completed his Ph.D. in Pharmaceutical Technology from Nagpur University,
India and his EMBA MS in Conflict Management from Sullivan University. He is Professor and
Associate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa,
Florida. With extensive experience in academia as well as industry, he has more than 100 publications,
two patents and two patent applications, twenty edited books published, including seven books
in Nanotechnology and six in Nutraceuticals and drug delivery systems. He has several books in cultural
studies and conflict management. He has received several National and International awards.
His recent assignment was Fulbright Senior Fellow in Indonesia for six months, where he traveled
in seven countries and lectured in more than twenty universities. He was a key note speaker at the
World Hindu Wisdom meeting in Bali, Indonesia, in June 2017 and co-chaired with the Governor
of Bali. Dr Yashwant Pathak is also a Professor of Global Health with the College of Public Health
at USF. Recently, his student completed a PhD in Global Health on homeopathy medicine and its
efficacy, a survey of 1274 patients in Pune in India. Dr Pathak is also an adjunct faculty member at
AirLangga University College of Public Health at Surabaya Indonesia.

Recenzii

"This book succeeds in presenting the challenges and barriers facing the field of nucleic acid delivery for therapeutic purposes, as well as the current status and main achievements of existing nanotechnologies in different therapeutic
areas".
- Doody's Review

Descriere

Gene therapy involves altering the genes in the body’s cells in an effort to treat or stop disease, instead of using drugs or surgery. This book discusses the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing.