HPLC in the Pharmaceutical Industry de Godwin W. Fong

HPLC in the Pharmaceutical Industry: Drugs and the Pharmaceutical Sciences

Godwin W. Fong

A practical guide for chemists in the pharmaceutical industry to making automated analyses of drugs that will meet the standards of regulatory agencies. Reviews the standard techniques of high-performance liquid chromatography, specialized detection methods, automation in pharmaceutical analysis, an

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Cuprins

Preface -- Contributors -- Part One -- Contemporary LC Techniques in Pharmaceutical Analysis -- 1. High Speed HPLC Using Short Columns Packed with 3 \xm Particles /Paul Kucera and Nicholas Licato -- 2. Microbore HPLC in Pharmaceutical Analysis /Thomas V Raglione and Richard A. Hartwick -- 3. Column Switching Techniques in Pharmaceutical Analysis /Francis K. Chow -- Part Two -- Specialized Detection Techniques -- 4. Liquid Chromatography /Electrochemistry in Pharmaceutical Analysis /Peter T. Kissinger and Donna M. Radzik -- 5. Radiochemical Quantitation: Considerations for HPLC /Jeff Quint and John F. Newton -- 6. HPLC with Computerized Diode Array Detection in Pharmaceutical Research /Ludwig Huber and H P. Fiedler -- 7. Design and Application of HPLC /FT-IR /Kathryn S. Kalasinsky and Victor F. Kalasinsky -- Part Three -- Automation in Pharmaceutical Analysis -- 8. Application of HPLC to Dissolution Testing of Solid Dosage Forms /William A. Hanson -- 9. Robotic Automation of HPLC Laboratories /Robin A. Felder -- Part Four -- HPLC of Peptides, Proteins, and Enantiomeric Drugs -- 10. Liquid Chromatographic Resolution of Enantiomers of Pharmaceutical Interest /Khanh H. Bui -- 11. HPLC of Proteins and Peptides in the Pharmaceutical Industry /Kalman Benedek and Joel K. Swadesh -- Index.

Notă biografică

GODWIN W. FONG is Director of Quality Control Laboratories for the Super pharm Corporation in Bayshore, New York. Previously, he was Assistant Director in Re¬search & Development at SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania. The author or coauthor of many publications and abstracts, Dr. Fong is a member of the American Chemical Society, American Association of Pharma¬ceutical Scientists, and American Association for the Advancement of Science, among others. Dr. Fong received the B.S. degree (1974) in chemistry from the State Uni¬versity of New York at Stony Brook, and Ph.D. degree (1980) in chemistry from the State University of New York at Buffalo. STANLEY K. LAM is Associate Professor of Laboratory Medicine and Director of the Drug Analysis and Special Chemistry Laboratory at the Albert Einstein College of Medicine, Bronx, New York. The author or coauthor of numerous scientific articles, book chapters, and abstracts, as well as editor of one book, Dr. Lam is a member of the American Chemical Society, American Association of Clinical Chemists, and American Association for the Advancement of Science. Dr. Lam received the B.A. degree (1974) in chemistry from California State University, Sacramento, and Ph.D. degree (1980) in chemistry from the State University of New York at Buffalo.

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