Cantitate/Preț
Produs
Total produse
Vezi coșul
Huntington’s Disease de Sophie V. Precious

Huntington’s Disease: Methods in Molecular Biology, cartea 1780

Editat de Sophie V. Precious, Anne E. Rosser, Stephen B. Dunnett
en Limba Engleză Hardback – iun 2018
This detailed book provides a laboratory manual and guidebook for the selection, implementation, and interpretation of a wide range of techniques in contemporary use in leading laboratories engaged in Huntington’s disease (HD) research worldwide. Only by understanding the pathology and pathogenic process at the fundamental molecular and cellular level can the research community expect to be able to slow or halt the disease process, repair the damage, and develop novel effective therapies to treat the symptoms of this condition, thus this volume collects the practical knowledge of its authors. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and invaluable, Huntington’s Disease aims to help scientists to significantly extend the breadth and quality of research in laboratories dedicated to mastering and controlling this devastating human condition.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 115962 lei  38-44 zile
  Springer – 25 iul 2019 115962 lei  38-44 zile
Hardback (1) 181079 lei  6-8 săpt.
  Springer – iun 2018 181079 lei  6-8 săpt.

Din seria Methods in Molecular Biology

  • 60% Nucleic Acid and Peptide Aptamers: Methods and Protocols
    Preț: 34795 lei
  • 23% Pheromone Signaling: Methods and Protocols
    Preț: 59856 lei
  • Engineering and Analyzing Multicellular Systems: Methods and Protocols
    Preț: 49679 lei
  • 20% Clinical Bioinformatics
    Preț: 88295 lei
  • Mitochondrial Regulation: Methods and Protocols
    Preț: 25204 lei
  • 5% Multiple Sclerosis: Methods and Protocols
    Preț: 71488 lei
  • 5% Bacterial Persistence: Methods and Protocols
    Preț: 71665 lei
  • 5% DNA-Protein Interactions: Principles and Protocols
    Preț: 72633 lei
  • 5% Methods in Mouse Atherosclerosis
    Preț: 73206 lei
  • 15% Cell Cycle Oscillators: Methods and Protocols
    Preț: 65004 lei
  • 18% TGF-β Signaling: Methods and Protocols
    Preț: 100455 lei
  • 5% Whole Genome Amplification: Methods and Protocols
    Preț: 71971 lei
  • 18% Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization
    Preț: 89567 lei
  • 15% Phospho-Proteomics: Methods and Protocols
    Preț: 65117 lei
  • 15% Candida Species: Methods and Protocols
    Preț: 64089 lei
  • 18% Induced Pluripotent Stem (iPS) Cells: Methods and Protocols
    Preț: 138603 lei
  • 5% Post-Transcriptional Gene Regulation
    Preț: 72759 lei
  • 20% In Vitro Embryogenesis in Higher Plants
    Preț: 82163 lei
  • 18% Yeast Functional Genomics: Methods and Protocols
    Preț: 95259 lei
  • 15% Statistical Analysis in Proteomics
    Preț: 64715 lei
  • 5% SiRNA Delivery Methods: Methods and Protocols
    Preț: 72348 lei
  • 18% Estrogen Receptors: Methods and Protocols
    Preț: 96497 lei
  • 5% Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II
    Preț: 71846 lei
  • Plant Bioinformatics: Methods and Protocols
    Preț: 39258 lei
  • 5% Breast Cancer: Methods and Protocols
    Preț: 73117 lei
  • 18% Endocannabinoid Signaling: Methods and Protocols
    Preț: 94315 lei
  • 23% Zebrafish: Methods and Protocols
    Preț: 86021 lei
  • 15% Activity-Based Proteomics: Methods and Protocols
    Preț: 63944 lei
  • 5% Drug Target miRNA: Methods and Protocols
    Preț: 103411 lei
  • 23% Computational Protein Design
    Preț: 88385 lei
  • SH2 Domains: Methods and Protocols
    Preț: 79216 lei
  • Cholesterol Homeostasis: Methods and Protocols
    Preț: 42362 lei
  • 5% The Immune Synapse: Methods and Protocols
    Preț: 42591 lei
  • Organ Regeneration: 3D Stem Cell Culture & Manipulation
    Preț: 59220 lei
  • 5% Innate Antiviral Immunity: Methods and Protocols
    Preț: 34562 lei
  • 19% Protein Engineering: Methods and Protocols
    Preț: 49188 lei
  • 5% Innate Immune Activation: Methods and Protocols
    Preț: 103884 lei
  • 5% Investigations of Early Nutrition Effects on Long-Term Health: Methods and Applications
    Preț: 52415 lei
  • 18% Planarian Regeneration: Methods and Protocols
    Preț: 207922 lei
  • 5% Epitope Mapping Protocols
    Preț: 127289 lei
  • Tissue Proteomics: Methods and Protocols
    Preț: 78993 lei
  • 5% Genetic Epidemiology: Methods and Protocols
    Preț: 133910 lei
  • 18% Plant Chemical Genomics: Methods and Protocols
    Preț: 136207 lei
  • 5% Lung Innate Immunity and Inflammation: Methods and Protocols
    Preț: 75266 lei
  • 5% Rational Drug Design: Methods and Protocols
    Preț: 37489 lei
  • 18% Microbiome Analysis: Methods and Protocols
    Preț: 136731 lei
  • 18% Computational Methods in Protein Evolution
    Preț: 110674 lei
  • 18% Electrophoretic Separation of Proteins: Methods and Protocols
    Preț: 137969 lei
  • 18% Microbial Metabolomics: Methods and Protocols
    Preț: 110211 lei
  • 18% SNAREs: Methods and Protocols
    Preț: 94669 lei

Preț: 181079 lei

Preț vechi: 220828 lei
-18% Nou

Puncte Express: 2716
Preț estimativ în valută:
34655€ • 35997$ • 28786£

Carte tipărită la comandă

Livrare economică 04-18 februarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781493978243
ISBN-10: 1493978241
Pagini: 794
Ilustrații: XV, 642 p. 111 illus., 74 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 1.35 kg
Ediția:1st ed. 2018
Editura: Springer
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:New York, NY, United States

Cuprins

Stereological Methods to Quantify Cell Loss in the Huntington’s Disease Human Brain.- Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells.- A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples.- Cellular Models: HD Patient-Derived Pluripotent Stem Cells.- Non-Mammalian Models of Huntington’s Disease.- Mouse Models of Huntington’s Disease.- Motor Assessment in Huntington’s Disease Mice.- Automated Operant Assessments of Huntington’s Disease Mouse Models.- Neurophysiological Assessment of Huntington’s Disease Model Mice.- Murine Models of Huntington’s Disease for Evaluating Therapeutics.- Generating Excitotoxic Lesion Models of Huntington’s Disease.- Large-Brained Animal Models of Huntington’s Disease: Sheep.- Minipigs as Large-Brained Animal Model for Huntington’s Disease: From Behavior and Imaging to Gene Therapy.- Non-Human Primate Models of Huntington’s Disease and Their Application in Translational Research.- In Vivo Multidimensional Brain Imaging in Huntington’s Disease Animal Models.- Magnetic Resonance Imaging in Huntington’s Disease.- Biofluid Biomarkers in Huntington’s Disease.- Assessing and Modulating Kynurenine Pathway Dynamics in Huntington’s Disease: Focus on Kynurenine 3-Monooxygenase.- Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington’s Disease.- Using Genomic Data to Find Disease-Modifying Loci in Huntington’s Disease (HD).-CRISPR/Cas9-Mediated Genome Editing for Huntington's Disease.- Methods for Assessing DNA Repair and Repeat Expansion in Huntington’s Disease.- Translating Antisense Technology into a Treatment for Huntington’s Disease.- Disease Modification through Trophic Factor Delivery.- Methods to Quantify Cell Signaling and GPCR Receptor Ligand Bias: Characterization of Drugs that Target the Endocannabinoid Receptors in Huntington’s Disease.- Dissection and Preparation of Human Primary Fetal Ganglionic Eminence Tissue for Research and Clinical Application.- Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells.- Quality Assessment and Production of Human Cells for Clinical Use.

Textul de pe ultima copertă

This detailed book provides a laboratory manual and guidebook for the selection, implementation, and interpretation of a wide range of techniques in contemporary use in leading laboratories engaged in Huntington’s disease (HD) research worldwide. Only by understanding the pathology and pathogenic process at the fundamental molecular and cellular level can the research community expect to be able to slow or halt the disease process, repair the damage, and develop novel effective therapies to treat the symptoms of this condition, thus this volume collects the practical knowledge of its authors. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and invaluable, Huntington’s Disease aims to help scientists to significantly extend the breadth and quality of research in laboratories dedicated to mastering and controlling this devastating human condition.

Caracteristici

Includes cutting-edge techniques for the study of Huntington's Disease Provides clear details essential for reproducible results Contains practical insights from experts in the field