Cantitate/Preț
Produs

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications: Chromatographic Science Series

Editat de Perry G. Wang, Weixuan He
en Limba Engleză Paperback – 22 mai 2017
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 58527 lei  43-57 zile
  CRC Press – 22 mai 2017 58527 lei  43-57 zile
Hardback (1) 156298 lei  43-57 zile
  CRC Press – 17 feb 2011 156298 lei  43-57 zile

Din seria Chromatographic Science Series

Preț: 58527 lei

Preț vechi: 68856 lei
-15% Nou

Puncte Express: 878

Preț estimativ în valută:
11200 11622$ 9362£

Carte tipărită la comandă

Livrare economică 17-31 martie

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781138113398
ISBN-10: 1138113395
Pagini: 616
Ilustrații: 293
Dimensiuni: 156 x 234 x 31 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Chromatographic Science Series


Cuprins

Aqueous Normal-Phase Chromatography: The Bridge between Reversed-Phase and HILIC. Application of the Calculated Physicochemical Property, Log D, to Hydrophilic Interaction Chromatography in the Bioanalytical Laboratory. HILIC Behavior of Reversed-Phase/Ion-Exchange Mixed-Mode Stationary Phases and Their Applications. Mechanisms Controlling the Separation and Retention of Proanthocyanidins and Other Plant Polyphenols in Hydrophilic Interaction Chromatography. Applications of Hydrophilic Interaction Chromatography to Food Analysis. Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry (HILIC-MS) of Paralytic Shellfish Poisoning Toxins, Domoic Acid, and Assorted Cyanobacterial Toxins. Application of HILIC for Polar Environmental Contaminants (Including Pharmaceuticals) in Aquatic Systems. Hydrophilic Interaction Chromatography–Mass Spectrometry: An Environmental Application. Clinical Applications of Hydrophilic Interaction Liquid Chromatography. Dimethylarginine Analysis by HILIC-MS/ MS and Its Applications in Clinical Chemistry and In Vivo Animal Models. Polar Functional Groups for HILIC Method. Analysis of Pharmaceutical Impurities Using Hydrophilic Interaction Liquid Chromatography. Fast In-Process Method for the Determination of Ioversol and Related Polar Compounds by Hydrophilic Interaction Chromatography (HILIC) and UPLC. Retention Behavior of Hydrazine Derivatives in HILIC Mode. HILIC Retention Behavior and Method Development for Highly Polar Basic Compounds Used in Pharmaceutical Synthesis. Retention of Polar Acidic and Basic Drugs by HILIC. Retention and Selectivity of Polar Stationary Phases for Hydrophilic Interaction Chromatography. HILIC-MS/MS for the Determination of Polar Bioactive Substances: Representative Applications in the Fields of Pharmacokinetics and Metabolic Profiling. Method Development and Analysis of Mono- and Diphosphorylated Nucleotides by HILIC HPLC-ESI-MS. Hydrophilic Interaction Liquid Chromatography–Based Enrichment Protocol Coupled to Mass Spectrometry for Glycoproteome Analysis. Development and Application of Methods for Separation of Carbohydrates by Hydrophilic Interaction Liquid Chromatography. Hydrophilic Interaction Liquid Chromatography in the Characterization of Glycoproteins. Analysis of Protein Glycosylation and Phosphorylation Using HILIC-MS.

Notă biografică

Perry G. Wang is currently Principal Scientist at Teleflex Medical in Wyomissing, Pennsylvania.

Recenzii

"[This book] contains a collection of case studies of practical importance, illustrating the development, optimization, and validation of HILIC methods for particular separation problems. Most chapters are clearly written, with emphasis on the experimental detail, and contain very useful up-to-date references. Researchers in analytical and bioanalytical chemistry may find this reference book useful."
—P. Jandera, Anal Bioanal Chem (2012) 404:11–12

Descriere

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.