Cantitate/Preț
Produs
Total produse
Vezi coșul
In Silico Methods for Predicting Drug Toxicity de Emilio Benfenati

In Silico Methods for Predicting Drug Toxicity: Methods in Molecular Biology, cartea 2425

Editat de Emilio Benfenati
en Limba Engleză Paperback – mar 2022
This fully updated book explores all-new and revised protocols involving the use of in silico models, particularly with regard to pharmaceuticals. Divided into five sections, the volume covers the modeling of pharmaceuticals in the body, toxicity data for modeling purposes, in silico models for multiple endpoints, a number of platforms for evaluating pharmaceuticals, as well as an exploration of challenges, both scientific and sociological. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice necessary for successful results. 

Authoritative and comprehensive, In Silico Methods for Predicting Drug Toxicity, Second Edition aims to guide the reader through the correct procedures needed to harness in silico models, a field which now touches a wide variety of research specialties.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (2) 77693 lei  6-8 săpt.
  Springer – 30 mai 2018 77693 lei  6-8 săpt.
  Springer Us – mar 2022 115429 lei  6-8 săpt.
Hardback (2) 109196 lei  6-8 săpt.
  Springer – 17 iun 2016 109196 lei  6-8 săpt.
  Springer Us – 22 feb 2022 158638 lei  6-8 săpt.

Din seria Methods in Molecular Biology

  • 70% Nucleic Acid and Peptide Aptamers: Methods and Protocols
    Preț: 26096 lei
  • 23% Pheromone Signaling: Methods and Protocols
    Preț: 59855 lei
  • 19% Plant-Pathogen Interactions: Methods and Protocols
    Preț: 57771 lei
  • Engineering and Analyzing Multicellular Systems: Methods and Protocols
    Preț: 49678 lei
  • 20% Clinical Bioinformatics
    Preț: 88293 lei
  • Mitochondrial Regulation: Methods and Protocols
    Preț: 25204 lei
  • 5% Multiple Sclerosis: Methods and Protocols
    Preț: 70873 lei
  • 5% Bacterial Persistence: Methods and Protocols
    Preț: 71049 lei
  • 5% DNA-Protein Interactions: Principles and Protocols
    Preț: 72009 lei
  • 5% Methods in Mouse Atherosclerosis
    Preț: 72575 lei
  • 15% Cell Cycle Oscillators: Methods and Protocols
    Preț: 64446 lei
  • 18% TGF-β Signaling: Methods and Protocols
    Preț: 99590 lei
  • 5% Whole Genome Amplification: Methods and Protocols
    Preț: 71354 lei
  • 18% Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization
    Preț: 88795 lei
  • 15% Phospho-Proteomics: Methods and Protocols
    Preț: 64558 lei
  • 15% Candida Species: Methods and Protocols
    Preț: 63539 lei
  • 18% Induced Pluripotent Stem (iPS) Cells: Methods and Protocols
    Preț: 137406 lei
  • 5% Post-Transcriptional Gene Regulation
    Preț: 72134 lei
  • 20% In Vitro Embryogenesis in Higher Plants
    Preț: 82163 lei
  • 18% Yeast Functional Genomics: Methods and Protocols
    Preț: 94440 lei
  • 15% Statistical Analysis in Proteomics
    Preț: 64158 lei
  • 5% SiRNA Delivery Methods: Methods and Protocols
    Preț: 71727 lei
  • 18% Estrogen Receptors: Methods and Protocols
    Preț: 95666 lei
  • 5% Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II
    Preț: 71229 lei
  • Plant Bioinformatics: Methods and Protocols
    Preț: 39257 lei
  • 5% Breast Cancer: Methods and Protocols
    Preț: 72490 lei
  • 18% Endocannabinoid Signaling: Methods and Protocols
    Preț: 93503 lei
  • 23% Zebrafish: Methods and Protocols
    Preț: 86019 lei
  • 15% Activity-Based Proteomics: Methods and Protocols
    Preț: 63395 lei
  • 5% Drug Target miRNA: Methods and Protocols
    Preț: 102521 lei
  • SH2 Domains: Methods and Protocols
    Preț: 79215 lei
  • Cholesterol Homeostasis: Methods and Protocols
    Preț: 42361 lei
  • 5% The Immune Synapse: Methods and Protocols
    Preț: 42590 lei
  • Organ Regeneration: 3D Stem Cell Culture & Manipulation
    Preț: 59219 lei
  • 5% Innate Antiviral Immunity: Methods and Protocols
    Preț: 34562 lei
  • 5% Synthetic Metabolic Pathways: Methods and Protocols
    Preț: 37270 lei
  • 19% Protein Engineering: Methods and Protocols
    Preț: 49188 lei
  • 5% Innate Immune Activation: Methods and Protocols
    Preț: 103882 lei
  • 18% Planarian Regeneration: Methods and Protocols
    Preț: 206129 lei
  • 5% Epitope Mapping Protocols
    Preț: 126192 lei
  • Tissue Proteomics: Methods and Protocols
    Preț: 78992 lei
  • 5% Genetic Epidemiology: Methods and Protocols
    Preț: 133907 lei
  • 18% Plant Chemical Genomics: Methods and Protocols
    Preț: 135031 lei
  • 5% Lung Innate Immunity and Inflammation: Methods and Protocols
    Preț: 75265 lei
  • 5% Rational Drug Design: Methods and Protocols
    Preț: 37488 lei
  • 18% Microbiome Analysis: Methods and Protocols
    Preț: 135552 lei
  • 18% Computational Methods in Protein Evolution
    Preț: 109722 lei
  • 18% Electrophoretic Separation of Proteins: Methods and Protocols
    Preț: 136778 lei
  • 18% Microbial Metabolomics: Methods and Protocols
    Preț: 109261 lei
  • 18% SNAREs: Methods and Protocols
    Preț: 93855 lei

Preț: 115429 lei

Preț vechi: 121504 lei
-5% Nou

Puncte Express: 1731
Preț estimativ în valută:
22093€ • 23026$ • 18391£

Carte tipărită la comandă

Livrare economică 06-20 ianuarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781071619629
ISBN-10: 1071619624
Pagini: 680
Ilustrații: XIV, 680 p. 244 illus., 215 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 1.19 kg
Ediția:2nd ed. 2022
Editura: Springer Us
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:New York, NY, United States

Cuprins

QSAR Methods.- PBPK Modeling to Simulate the Fate of Compounds in Living Organisms.- Pharmacokinetic Tools and Applications.- In Silico Tools and Software to Predict ADMET of New Drug Candidates.- Development of In Silico Methods for Toxicity Prediction in Collaboration between Academia and the Pharmaceutical Industry.- Emerging Bioinformatics Methods and Resources in Drug Toxicology.- In Silico Prediction of Chemically-Induced Mutagenicity: A Weight of Evidence Approach Integrating Information from QSAR Models and Read-Across Predictions.- In Silico Methods for Chromosome Damage.- In Silico Methods for Carcinogenicity Assessment.- In Silico Models for Developmental Toxicity.- In Silico Models for Repeated-Dose Toxicity (RDT): Prediction of the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) for Drugs.- In Silico Models for Predicting Acute Systemic Toxicity.- In Silico Models for Skin Sensitization and Irritation.- In Silico Models for Hepatotoxicity.- Machine Learning Models for Predicting Liver Toxicity.- Implementation of In Silico Toxicology Protocols in Leadscope.- Use of Lhasa Limited Products for the In Silico Prediction of Drug Toxicity.- Using VEGAHUB within a Weight-of-Evidence Strategy.- MultiCASE Platform for In Silico Toxicology.- Adverse Outcome Pathways as Versatile Tools in Liver Toxicity Testing.- The Use of In Silico Methods for the Regulatory Toxicological Assessment of Pharmaceutical Impurities.- Computational Modeling of Mixture Toxicity.- In Silico Methods for Ecological Risk Assessment: Principles, Tiered Approaches, Applications, and Future Perspectives.- Increasing the Value of Data within a Large Pharmaceutical Company through In Silico Models.

Textul de pe ultima copertă

This fully updated book explores all-new and revised protocols involving the use of in silico models, particularly with regard to pharmaceuticals. Divided into five sections, the volume covers the modeling of pharmaceuticals in the body, toxicity data for modeling purposes, in silico models for multiple endpoints, a number of platforms for evaluating pharmaceuticals, as well as an exploration of challenges, both scientific and sociological. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice necessary for successful results. 

Authoritative and comprehensive, In Silico Methods for Predicting Drug Toxicity, Second Edition aims to guide the reader through the correct procedures needed to harness in silico models, a field which now touches a wide variety of research specialties.

Caracteristici

Includes cutting-edge techniques Provides step-by-step detail essential for reproducible results Contains key implementation advice from the experts