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Pharmacogenomics in Drug Discovery and Development: Methods in Molecular Biology, cartea 2547

Editat de Qing Yan
en Limba Engleză Hardback – 7 sep 2022
This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. 

Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.
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Specificații

ISBN-13: 9781071625729
ISBN-10: 1071625721
Pagini: 616
Ilustrații: XIV, 616 p. 54 illus., 47 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 1.31 kg
Ediția:3rd ed. 2022
Editura: Springer Us
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:New York, NY, United States

Cuprins

Target Discovery for Drug Development Using Mendelian Randomization.- Human Leukocyte Antigen (HLA) Testing in Pharmacogenomics.- Pharmacogenomics in Targeted Therapy and Supportive Care Therapies for Cancer.- Pharmacogenomics in Cytotoxic Chemotherapy of Cancer.- Management of Side Effects in the Personalized Medicine Era: Chemotherapy-Induced Peripheral Neuropathy.- The Yin-Yang Dynamics in Cancer Pharmacogenomics and Personalized Medicine.- Design of Personalized Neoantigen RNA Vaccines Against Cancer Based on Next Generation Sequencing Data.- COVID-19 Pharmacotherapy: Drug Development, Repurposing of Drugs, and the Role of Pharmacogenomics.- Pharmacogenomics Informs Cardiovascular Pharmacotherapy.- Pharmacogenomic Screening of Patient-Specific hiPSC-Derived Cardiomyocyte Drug Candidates Using High-Throughput Calcium Imaging.- The Yin-Yang Dynamics in Cardiovascular Pharmacogenomics and Personalized Medicine.- GTPgS Assay for Measuring Agonist-Induced Desensitization of Two Human Polymorphic Alpha2B-Adrenoceptor Variants.- Pharmacogenomics of Alzheimer’s Disease: Novel Strategies for Drug Utilization and Development.- Pharmacogenetics of Antipsychotic Treatment in Schizophrenia.- The Pharmacogenetic Impact on the Pharmacokinetics of ADHD Medications.- Pharmacogenetics of Addiction Therapy.- Pharmacogenomics of Opioid Treatment for Pain Management.- The Role of Pharmacogenomics in Postoperative Pain Management.- Pharmacogenetics of Drug Therapies in Rheumatoid Arthritis.- Pharmacogenomics in Children.- Genetic Ancestry Inference for Pharmacogenomics.

Textul de pe ultima copertă

This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. 

Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.

Caracteristici

Includes cutting-edge techniques Provides step-by-step detail essential for reproducible results Contains key implementation advice from the experts

Recenzii

From the reviews:
"This volume in the Methods in Molecular Biology series covers pharmacogenomics in drug discovery. … The book is intended for scientists in academic, industrial, and health care settings who are striving to transform disease treatment into disease prevention. … The advanced technologies are presented in a very detail manner, even including step-by-step protocols. … By covering topics from individual molecules to systemic diseases … this book provides an overview of current knowledge on the use of pharmacogenomics in therapeutics of disease." (Xiaobo Zhong, Doody’s Review Service, July, 2008)