Cantitate/Preț
Produs

Protein Microarray for Disease Analysis: Methods and Protocols: Methods in Molecular Biology, cartea 723

Editat de Catherine J. Wu
en Limba Engleză Hardback – 3 mar 2011
Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response.  In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease.  These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes.  Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
 
Practical and cutting-edge,  Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 87539 lei  6-8 săpt.
  Humana Press Inc. – 23 aug 2016 87539 lei  6-8 săpt.
Hardback (1) 64379 lei  6-8 săpt.
  Humana Press Inc. – 3 mar 2011 64379 lei  6-8 săpt.

Din seria Methods in Molecular Biology

Preț: 64379 lei

Preț vechi: 75740 lei
-15% Nou

Puncte Express: 966

Preț estimativ în valută:
12325 12811$ 10219£

Carte tipărită la comandă

Livrare economică 05-19 februarie 25

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781617790423
ISBN-10: 1617790427
Pagini: 388
Ilustrații: XIII, 373 p.
Dimensiuni: 178 x 254 x 30 mm
Greutate: 0.88 kg
Ediția:2011
Editura: Humana Press Inc.
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:Totowa, NJ, United States

Public țintă

Professional/practitioner

Cuprins

Detecting and Quantifying Multiple Proteins in Clinical Samples in High-Throughput Using Antibody Microarrays.- Analysis of Serum Protein Glycosylation with Antibody-Lectin Microarray for High-Throughput Biomarker Screening.- Antibody Suspension Bead Arrays.- Reverse Protein Arrays Applied to Host-Pathogen Interaction Studies.- Identification and Optimization of DNA Aptamer Binding Regions Using DNA Microarrays.- Recombinant Lectin Microarrays for Glycomic Analysis.- Recombinant Antigen Microarrays for Serum/Plasma Antibody Detection.- SPOT Synthesis as a Tool to Study Protein-Protein Interactions.- Native Antigen Fractionation Protein Microarrays for Biomarker Discovery.- Immunoprofiling Using NAPPA Protein Microarrays.- High-Throughput Mammalian Two-Hybrid Screening for Protein-Protein Interactions Using Transfected Cell Arrays (CAPPIA).- Protein-Protein Interactions: An Application of Tus-Ter Mediated Protein Microarray System.- Kinase Substrate Interactions.- A Functional Protein Microarray Approach to Characterizing Posttranslational Modifications on Lysine Residues.- Multiplexed Detection of Antibodies Using Programmable Bead Arrays.- A Co-Precipitation-Based Validation Methodology for Interactions Identified Using Protein Microarrays.- Development of Expression-Ready Constructs for Generation of Proteomic Libraries.- Reverse Phase Protein Microarrays: Fluorometric and Colorimetric Detection.- Förster Resonance Energy Transfer Methods for Quantification of Protein-Protein Interactions on Microarrays.- Label-Free Detection with Surface Plasmon Resonance Imaging.- Data Processing and Analysis for Protein Microarrays.- Database Resources for Proteomics-Based Analysis of Cancer.

Recenzii

From the reviews:
“This is a well-illustrated book with concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to detect disease. … The book is intended for scientists, but it also will be of immense help to graduate students and researchers interested protein microarrays. … a well-done resource on the methodologies currently used in protein microarrays to promote a cell-level biochemical understanding of human disease processes that could revolutionize drug development.” (Omer Iqbal, Doody’s Review Services, July, 2011)

Textul de pe ultima copertă

Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response.  In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease.  These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes.  Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
 
Practical and cutting-edge,  Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.

Caracteristici

Serves as a toolbox of methodologies currently used in the field of protein microarray study Features step-by-step protocols ready for the lab Contains expert tips and vital implementation advice to ensure success Includes supplementary material: sn.pub/extras